Investigating sleep in brain organoids and mice
University of Amsterdam·Amsterdam·Wo·geplaatst 15 september 2024·nog niet gecontroleerd
Vacaturetekst
The Cognitive and Systems Neuroscience group (with dr. Umberto Olcese) from the University of Amsterdam is seeking a motivated MSc intern to work on a research project that aims to investigate sleep in brain organoids and mice.
Project: Sleep is essential for everyday life, and its disturbances can serve as early warning signs of neurodegenerative diseases such as Parkinson’s Disease. Sleep is currently studied on animals or in 2D cultures, neither of which are informative of individual sleep habits. Brain organoids are self-organized cell culture models derived from human stem cells or induced pluripotent stem cells (iPSCs). They have been used as in vitro models for investigating the molecular and neural mechanisms of neurological diseases including autism spectrum disorder and Alzheimer’s disease. However, it is unknown whether brain organoids have the potential as a model for sleep research. We will combine cutting-edge techniques in systems neuroscience and stem cell biology to demonstrate a new human-derived in vitro sleep model that potentially contribute to the early diagnosis for neurodegenerative diseases.
Responsibilities
Conduct the behavioral training on mice
Assist in maintenance of brain organoids
Analyze neural imaging and behavioral data
Collect information (e.g., literature review, handbook reading) for problem solving
Requirements
Essential:
Preferred experience (a plus):
What you will gain
Mentorship and guidance in research methodologies.
Hands-on experience in neuroscience and cell biology experiments.
Development of data analysis skills.
Networking opportunities with researchers across various disciplines.
Details
Starting date: September 2024 (Preferred)
Duration: Minimum of 6 months
Location: Amsterdam Science Park
Supervision: You will be supervised by Dr. Junying Wang (Postdoc) in Dr. Umberto Olcese’s lab.
How to Apply: Please send your CV and cover letter to Junying Wang at [staat bij de werkgever] with the subject line “Internship Application – [Your Name]”. For more information, feel free to contact the same email address.
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Bron
Wij zagen deze vacature op de website van de werkgever. Daar staat de actuele tekst; wijzigingen na 30 juli 2026 zien wij pas bij de volgende controle. Wij hebben deze vacature na het vinden nog niet opnieuw gecontroleerd, dus hij kan inmiddels vervuld zijn.